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Advantage of AH-801-AI:
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1.
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AH-801-AI can promote mice in either NREM or REM sleep stage percentage.
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AH-801-AI can promote EPO and neurotrophic factors protein in different brain area (cortex, hippocampus & hypothalamus).
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AH-801-AI can activate autophagy during sleep stage.
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AH-801-AI go through natural sleep mechanism to promote memory performance and consolidation by autophagy pathway as natural sleep aid for insomnia, which quite different from current GABA receptor agonist sedatives - Benzodiazepine.
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5.
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AH-801-AI is a evolutional insomnia drug candidate for aging related insomnia population.
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Fig. Effect of AH-801-AI on sleep cycle distribution by EEG/EMG scoring in C57BL/6JNarl mice.
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Global market for Insomnia
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Global Data 2015
Insomnia is the most common sleep disorder and is believed to affect 35% of the global population.
Grand View Research 2017 Oct
The global insomnia therapeutics market size was valued at USD 2.18 billion in 2016 and is expected to grow at a CAGR of 5.3% over the forecast period.
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